The Critical Importance of Pharmacy Source for Oxycodone Safety In the current opioid crisis environment — specifically the epidemic of counterfeit prescription opioid tablets contaminated with illicitly manufactured fentanyl — the question of where oxycodone is obtained has become a direct, concrete matter of survival. The counterfeit opioid reality: The . . . Read more
Cancer Pain: The Clinical and Ethical Case for Opioid Analgesia Cancer pain represents one of the clearest medical and ethical cases for opioid analgesic therapy — a context where the imperative to relieve severe, life-altering pain is unambiguous and where the long-term concerns about opioid dependence that govern chronic non-cancer . . . Read more
The Safety Imperative in Oxycodone Therapy Oxycodone’s potent mu-opioid receptor agonism that makes it effective for severe pain also produces a clinically significant adverse effect and drug interaction profile that requires systematic management from the initiation of therapy through its entire duration. For patients receiving oxycodone through licensed pharmacies under . . . Read more
Extended-Release Oxycodone: Clinical Purpose and Patient Selection OxyContin — the brand name for controlled-release oxycodone — was introduced by Purdue Pharma in 1996 with FDA approval for management of moderate-to-severe pain when a continuous, around-the-clock opioid analgesic is needed for an extended period of time. Generic extended-release oxycodone products have . . . Read more
Chronic Pain as a Medical Condition Warranting Opioid Therapy Chronic pain — pain persisting beyond the expected healing period, conventionally defined as lasting three months or more — affects approximately 50 million American adults and represents the leading cause of disability and reduced quality of life in the United States. . . . Read more
Introduction: Oxycodone in Modern Pain Medicine Oxycodone is a semi-synthetic opioid analgesic that has served as a cornerstone of moderate-to-severe pain management for over a century — first synthesized in Germany in 1916 and introduced to clinical practice as an improvement on the oral analgesic limitations of morphine. Today, oxycodone . . . Read more